Santi Nonell Marrugat, PhD
Head of APPLIGHTCHEM Group - Professor - ICREA Academia
+34932672000
RESEARCH LINES
- Biological photochemistry
- Photodynamic therapy and theranostic applications of light
- Photofunctional molecules and nanomaterials
- Photoprotective sunscreens
COORDINATOR:
School of Engineering
Applied Photobiological Chemistry
Specialised research in biomedical applications (antimicrobial resistance with phototherapy) and development of theragnostics in the diagnosis and treatment of tumours.
MANAGER:
Photochemistry Laboratory
It focuses its research activity on photochemistry and the interrelationships of light with molecules, materials and biological systems. It carries out RDI activities and knowledge and technology transfer in solar photoprotection, cancer photochemotherapy, photoantimicrobial therapies and fluorescence imaging.
LATEST PROJECTS
Theranostic photosensitizers (Phosphorescence-guided surgery combined with photodynamic therapy)
Photodynamic therapy uses harmless light in live cells and animal to activate non- toxic photosensitive chemicals photosensitizers to generate cytotoxic species for malignant cell eradication (cancer cells, bacterial infections).
Funding Agency:
Research Group Link:
Applied Photobiological Chemistry (AppLightChem)
PhotoSMS (Terapia fotodinámica en cancer)
Nanosistemas multifuncionales autoensamblados para aplicaciones fototeranósticas.
Funding Agency:
Research Group Link:
Applied Photobiological Chemistry (AppLightChem)
Materials Engineering (GEMAT)
Chemical & Synthetic Biology for Biotherapies (ChemSynBio)
LIGHT4LUNGS (Fotones y radicales de O2 para combatir infecciones resistentes a antibioticos)
Desarrollo de un aerosol innovador que alimenta con fotones las vías respiratorias generando radicales de oxígeno para combatir infecciones de las vías respiratorias resistentes al uso de antibióticos.
Funding Agency:
Research Group Link:
Applied Photobiological Chemistry (AppLightChem)
LINKED NEWS
Doctoral thesis
New Antimicrobial Photodynamic Platform
05/12/2023
Dr Andrea Mussini recently defended his doctoral thesis, conducted jointly between IQS and the University of Parma, on new delivery systems for protein-based antimicrobial photodynamic therapies.
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Interview
Dr Santi Nonell, the First ICREA Researcher at IQS
08/05/2023
Interview with Dr Santi Nonell, tenured professor at the IQS School of Engineering and the university’s first researcher to form part of the ICREA Academia community for excellence in research at Catalan universities.
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Interview
Photodynamic Therapies to Combat Antimicrobial Resistance
03/02/2023
“IQS is conducting mechanistic characterization studies of light-emitting particles and the mechanism of light-induced cell death within the Light4Lungs consortium”
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Research
Self-Assembled Nanosystems for Phototheranostic Applications
24/11/2021
Researchers from IQS and UAM collaborate in the PhotoSMS project to develop "all-in-one" photodynamic agents capable of forming nanostructures with phototherapeutic activity.
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Doctoral thesis
Photosensitive Targeted Nanocarriers for Selective Delivery of Photodynamic Therapy
29/07/2021
Dr Elena de las Heras recently defended her doctoral thesis at IQS, in which she has designed and developed new photo-immuno-chemo-nanotransporters, which have shown high photodynamic activity against tumour cells and are effective and safe for the photodynamic delivery of doxorubicin on demand.
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