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School of Engineering

Applied Photobiological Chemistry

(AppLightChem)

AppLightChem is a research group that specializes in the biomedical applications and chemical aspects of photonics.

 

It focuses its research and transfer activities on solar photoprotection, cancer photochemotherapy, photoantimicrobial therapies and fluorescence imaging. AppLightChem develops advanced chemical technologies for photoprotection, diagnosis and treatment of diseases with light-activated drugs.

 

The group is an international leader in its field and has a significant number of international and corporate collaborations.

In this environment, AppLightChem carries out its RD and technology transfer activities on the following areas:

 

  • Biological photochemistry
  • Photofunctional molecules and nanomaterials
  • New strategies in antimicrobial photodynamic therapy: genetically encoded photosensitisers, peptide-photosensitiser conjugates and multi-cationic photosensitisers
  • Photodynamic therapy and theragnostic applications of light

 

  • New strategies in singlet oxygen detection using fluorescence probes
  • Photoprotective solar filters
  • Photoelectrochemistry of nanostructured semiconductive electrodes

COORDINATOR:

Santi Nonell Marrugat, PhD

Head of APPLIGHTCHEM Group - Professor
+34932672000
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MEMBERS:

Ms Mireia Jordà Redondo

Applied Anlaytical Chemistry Dpt.
+34932672000

EXTERNAL COLABORATORS

Giovanni Romano, PhD

Università degli Studi di Firenze

Nelly Henry, PhD

Sorbonne Université, Campus Pierre et Marie Curie

Emilio Palomares, PhD

Institut Català d’Investigació Química (ICIQ)

Elena Reddi, PhD

Università di Padova

Karas Kadioglu, PhD

Liverpool University

Glyn Taylor, PhD

Cardiff Scintigraphics Limited (i2c)

FACILITIES

Photochemistry Laboratory

LINKED NEWS

Interview

Theranostic Photosensitizing Agents for Phosphorescence-Guided Surgery

30/09/2022
"It is essential to have adequate tools in order to study complex systems, and photonics is an ideal discipline considering its non-invasive nature, occupying an essential place in research"
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Research

Self-Assembled Nanosystems for Phototheranostic Applications

24/11/2021
Researchers from IQS and UAM collaborate in the PhotoSMS project to develop "all-in-one" photodynamic agents capable of forming nanostructures with phototherapeutic activity.
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Doctoral thesis

Photosensitive Targeted Nanocarriers for Selective Delivery of Photodynamic Therapy

29/07/2021
Dr Elena de las Heras recently defended her doctoral thesis at IQS, in which she has designed and developed new photo-immuno-chemo-nanotransporters, which have shown high photodynamic activity against tumour cells and are effective and safe for the photodynamic delivery of doxorubicin on demand.
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LATEST PROJECTS

Theranostic photosensitizers (Phosphorescence-guided surgery combined with photodynamic therapy)

Photodynamic therapy uses harmless light in live cells and animal to activate non- toxic photosensitive chemicals photosensitizers to generate cytotoxic species for malignant cell eradication (cancer cells, bacterial infections).
Funding Agency:
Research Group Link:
Applied Photobiological Chemistry (AppLightChem)

PhotoSMS (Terapia fotodinámica en cancer)

Nanosistemas multifuncionales autoensamblados para aplicaciones fototeranósticas.
Funding Agency:
Research Group Link:
Applied Photobiological Chemistry (AppLightChem)
Materials Engineering (GEMAT)

LIGHT4LUNGS (Fotones y radicales de O2 para combatir infecciones resistentes a antibioticos)

Desarrollo de un aerosol innovador que alimenta con fotones las vías respiratorias generando radicales de oxígeno para combatir infecciones de las vías respiratorias resistentes al uso de antibióticos.
Funding Agency:
Research Group Link:
Applied Photobiological Chemistry (AppLightChem)
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