Photochemistry Laboratory
It focuses its research activity on photochemistry and the interrelationships of light with molecules, materials and biological systems. It carries out RDI activities and knowledge and technology transfer in solar photoprotection, cancer photochemotherapy, photoantimicrobial therapies and fluorescence imaging.
It develops advanced chemical technologies for photoprotection, diagnosis and treatment of diseases with light-activated drugs.
- Development and characterisation of photoactive materials and molecules
- Development of photoactivatable drugs
- Development of solar photoprotectors
- Study of drug photodegradation
- Laser instrumentation for kinetic studies: luminescence lifetimes, FRET assays, flash photolysis, etc.
- Singlet oxygen detection system: characterisation of antioxidants, photoinactivation of viruses and bacteria, photodegradation of dyes
- System for characterisation of luminescent materials in the near infrared (NIR)
- Photoacoustic material characterisation system
- Cryogenic detectors for low temperature optical measurements
EQUIPMENT
Solar simulator; Atlas; Suntest XLS+
Photoreactor; Luzchem Research Inc.; LZC-ICH2
Lifetime UV-VIS-NIR Fluorimeter; PicoQuant; Fluotime 200
Spectrophotometer UV-VIS-NIR; Agilent Technologies; Cary 6000i
Spectrofluorimeters; Perkin Elmer LS-45; Horiba Jobin Yvon Fluoromax-4
Laser kinetic spectrophotometer with optical and photoacoustic detection
Singlet Oxygen Detection System (NIR phosphorescence)
MANAGER
Santi Nonell Marrugat, PhD
Head of APPLIGHTCHEM Group - Professor - ICREA Academia
+34932672000
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BUSINESS SOLUTION AREAS
RESEARCH GROUP
School of Engineering
Applied Photobiological Chemistry
Specialised research in biomedical applications (antimicrobial resistance with phototherapy) and development of theragnostics in the diagnosis and treatment of tumours.
LINKED NEWS
Research
Self-Assembled Nanosystems for Phototheranostic Applications
24/11/2021
Researchers from IQS and UAM collaborate in the PhotoSMS project to develop "all-in-one" photodynamic agents capable of forming nanostructures with phototherapeutic activity.
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Doctoral thesis
Photosensitive Targeted Nanocarriers for Selective Delivery of Photodynamic Therapy
29/07/2021
Dr Elena de las Heras recently defended her doctoral thesis at IQS, in which she has designed and developed new photo-immuno-chemo-nanotransporters, which have shown high photodynamic activity against tumour cells and are effective and safe for the photodynamic delivery of doxorubicin on demand.
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News
Analysis of nitrosamines, nitrites, and nitrates in drugs
08/01/2021
In July 2018, public health authorities became aware of the presence of the N-nitrosodimethylamine (NDMA) impurity in Valsartan batches for the first time. In the following months, other nitrosamines in drugs were detected from the same family (sartans), such as Ibersartan or Losartan, and in other drugs such as pioglitazone, ranitidine, and metformin.
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