Antoni Planas Sauter, PhD
Head of GQBB Group - Professor - Fellow of the Royal Academy of Sciences and Arts of Barcelona
+34932672000
RESEARCH LINES
- Protein engineering and enzymology of glycosidases, glycosyltransferases and carbohydrate esterases.
- Therapeutic targets in infectious diseases
- Biocatalysis: enzyme re-engineering, directed enzyme evolution
- Genetic and metabolic engineering in bacteria, yeast and microalgae
- Amyloid proteins in neurodegenerative diseases
COORDINATOR:
School of Engineering
Biological and Biotechnological Chemistry
Its activity focuses on the identification and molecular analysis of proteins and enzymes as therapeutic targets, together with the design and application of enzymes in biocatalysis and biotechnology with microorganisms.
MANAGER:
Bioprocess Pilot Plant
Bioprocessing infrastructure and equipment for the development, optimisation, scale-up and manufacturing of test batches. Suitable for microorganisms cultures (bacteria, yeasts and fungi) in batch and fed-batch and in aerobic or anaerobic conditions. Class 1 organisms (non-pathogenic). Includes downstream operations for the first stages of bioproduct isolation.
Biochemistry Laboratory
The Biochemistry Laboratory focuses its research on Carbohydrate Active Enzymes (CAZymes) involved in the biosynthesis, modification and degradation of glycans and glycoconjugates, from fundamental aspects of their mechanism, specificity and regulation to their applications in biocatalysis, synthetic biology and as therapeutic targets in infectious diseases.
LATEST PROJECTS
Glycoengin (Engineered Glycozymes in biocatalysis, metabolic engineering and bio-orthogonal chemical biology)
Application of Carbohydrate Active Enzyme (or Glycozymes) by means of protein engineering and metabolic engineering to the generation of technological tools in glycoscience and the production of high-value glicoconjugates for health, nutraceuticals and food sectors.
Funding Agency:
Research Group Link:
Biological and Biotechnological Chemistry (GQBB)
PaCosValor (Producción biotecnológica de oligosacaridos de quitosano con estructura definida como inmunoestimulantes)
Escalado y valorización dequitooligosacáridos parcialmente acetilados como nutracéuticos que estimulan el sistema inmunológico.
Funding Agency:
Research Group Link:
Biological and Biotechnological Chemistry (GQBB)
GLYCODESIGN (Ingenieria enzimática)
Ingeniería de proteínas e ingeniería metabólica de glicozimas para la producción de glicanos y glicoconjugados bioactivos orientados a aplicaciones biomédicas
Funding Agency:
Research Group Link:
Biological and Biotechnological Chemistry (GQBB)
LINKED NEWS
Doctoral thesis
A Platform for Sustainable Glycolipid Production
13/09/2023
Dr Bernat Miró recently completed his doctoral thesis at IQS, in which he explored the genetic and metabolic modification of microalgae for the sustainable production of bioactive glycolipids with high added value.
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Doctoral thesis
Metabolic Engineering for Glycolipid Production
04/05/2023
Dr Marc Caballé recently defended his doctoral thesis at IQS, in which he explored metabolic engineering as a biological alternative for the production of glycolipids with high biological interest such as α-galactosylceramide.
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News
Computational Biology: discovering and optimizing new products
31/03/2023
The Bioinformatics and Molecular Modeling unit within the IQS Biochemistry Laboratory works on the development and application of computational biology, artificial intelligence, and simulation methods for the discovery and optimization of high added value products for application in various sectors of activity.
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Editorial
Dr Antoni Planas i Sauter, Scholar with the Royal Academy of Sciences and Arts of Barcelona
27/06/2022
Dr Antoni Planas i Sauter has been named a scholar with the 3rd Chemistry section of the RACAB, a very important honour for IQS and one that recognizes the outstanding career of one of its professors.
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News
IQS Sponsors the First Biomedical Glycoscience Summer School
20/06/2022
IQS sponsored the inaugural edition of the Biomedical Glycoscience Summer School, organized by the Specialized Carbohydrates Group with the RSEQ in which over 40 researchers in the field of glycosciences participated.
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Research
Biostimulants and Alternative Proteins
15/06/2022
The CTPTI Bioprocess Pilot Plant at IQS has recently carried out various collaborative efforts with companies on projects and developing innovative products in the fields of biostimulants and alternative proteins.
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News
Givaudan visits the IQS Bioprocess Plant
12/05/2022
The representatives from Givaudan Ibérica were able to take a guided tour of the Bioprocess Pilot Plant, led by Dr Planas himself, where they discovered the possibilities offered by this facility first-hand.
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Doctoral thesis
Obtaining HMOs through Enzymatic Synthesis
16/03/2022
Dr. Mireia Castejón recently defended her doctoral thesis at IQS, where she has managed to obtain the tetrasaccharide compound lacto-N-tetraose, present in breast milk, by enzymatic synthesis. This opens the door to obtaining new biocatalysts for the synthesis of HMO oligosaccharides by this route.
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News
IQS Teaches its First Bioprocesses Course for Companies
17/02/2022
The company Syva, specialized in animal health, has received the first training course in the design and optimization of bioprocesses, organized by the IQS Bioprocess Pilot Plant.
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News
Protein hydrolysates for animal feed
04/04/2021
The Biochemistry Laboratory at IQS has analysis techniques to verify if the protein hydrolysates comply with European standards which limits the presence of proteins with a molecular weight over 10kDa.
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Doctoral thesis
New biological platform for the production of glycoglycerolipids
08/01/2021
In her doctoral thesis carried out in the Department of Bioengineering of IQS, Dr Núria Orive designed different metabolic engineering strategies to increase the production of glycoglycerolipids, interesting products due to their potential use as vaccine adjuvants or tumor suppressors.
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