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Biochemistry Laboratory

The Biochemistry Laboratory focuses its research on Carbohydrate Active Enzymes (CAZymes) involved in the biosynthesis, modification and degradation of glycans and glycoconjugates, from fundamental aspects of their mechanism, specificity and regulation to their applications in biocatalysis, synthetic biology and as therapeutic targets in infectious diseases.

The laboratory covers disciplines from Chemistry, Biology and Engineering to address its R&D projects in glycosciences with applications in biotechnology and biomedicine.

  • Biocatalysis: development of processes and enzymes for the enzymatic synthesis of value-added products
  • Protein engineering: approaches to rational and targeted evaluation
  • Bioinformatics and molecular modelling
  • Metabolic engineering for metabolite production
  • Use of enzymes in the synthesis of bioactive products and pharmaceutical intermediates

 



                        
  • Characterisation of enzyme activity
  • Analysis of proteins and protein hydrolyzates. Molecular weight distribution
  • Determination of enzyme activity
  • Bioanalysis: proteins and nucleic acids

EQUIPMENT

AKTA and GILSON protein chromatographs for protein purification

HPLC chromatographs with UV, refractive index and fluorescence detectors

HPLC chromatograph and MS single Q

UV/Vis Spectrophotometer

Spectrofluorimeter

Microplate readers with UV/Vis, fluorescence

Differential scanning microcalorimeter, DSC

Isothermal titration microcalorimeter

Refrigerated centrifuges

Automatic titrator

PCR thermal cyclers

Cell disruptor

Sonicator

Electroporates

Orbital and CO2 incubators

Cell culture incubators

Laminar flow cabinets

-80ºC Freezer

Equipos de electroforesis de proteínas en gel

Liofilizador

Robot BRAVO

7L Brau Bioreactor with probes and control system

MANAGER

Antoni Planas Sauter, PhD

Head of GQBB Group - Professor - Fellow of the Royal Academy of Sciences and Arts of Barcelona
+34932672000
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RESEARCH GROUP

GQBB

Grup de Química Biològica i Biotecnològica

School of Engineering

Biological and Biotechnological Chemistry

Its activity focuses on the identification and molecular analysis of proteins and enzymes as therapeutic targets, together with the design and application of enzymes in biocatalysis and biotechnology with microorganisms.

LINKED NEWS

Interview

Interview with Dr Marçal Gallemí

13/09/2023
"The Beatriu de Pinós Grant gives me the opportunity to get involved in a research project on scaling bioprocesses that has the potential for technology transfer"
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Doctoral thesis

A Platform for Sustainable Glycolipid Production

13/09/2023
Dr Bernat Miró recently completed his doctoral thesis at IQS, in which he explored the genetic and metabolic modification of microalgae for the sustainable production of bioactive glycolipids with high added value.
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7 Questions for...

PAU LEIVAR

04/04/2021
Profesor del Departamento de Bioingeniería i miembro del Grupo de Química Biológica y Biotecnología (GQBB) de IQS School of Engineering.
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News

Protein hydrolysates for animal feed

04/04/2021
The Biochemistry Laboratory at IQS has analysis techniques to verify if the protein hydrolysates comply with European standards which limits the presence of proteins with a molecular weight over 10kDa.
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7 Questions for...

MAGDA FAIJES

05/02/2021
Dra. Magda Faijes, Profesora del Departamento de Bioingeniería y miembro del Grupo de Química Biológica y Biotecnología de IQS School of Engineering.
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Doctoral thesis

New biological platform for the production of glycoglycerolipids

08/01/2021
In her doctoral thesis carried out in the Department of Bioengineering of IQS, Dr Núria Orive designed different metabolic engineering strategies to increase the production of glycoglycerolipids, interesting products due to their potential use as vaccine adjuvants or tumor suppressors.
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