Bioprocess Pilot Plant
Bioprocessing infrastructure and equipment for the development, optimisation, scale-up and manufacturing of test batches. Suitable for microorganisms cultures (bacteria, yeasts and fungi) in batch and fed-batch and in aerobic or anaerobic conditions. Class 1 organisms (non-pathogenic). Includes downstream operations for the first stages of bioproduct isolation.
It features a surface area of 130 m2 including:
- Bioprocessing space, which houses the 144 L bioreactor, auxiliary services and process equipment (DSP) including cell disruption, centrifugation, microfiltration, ultrafiltration and lyophilisation.
- Reagents and Product storage, with a 4ºC cold chamber and a -20C chest for the storage of samples, culture media and production batches that require cold preservation.
- Auxiliary Laboratory, for the preparation of inoculums, culture media and analytical techniques. Equipped with a laminar flow cabinet, fume hood, incubators, baths, centrifuges, spectrophotometer, analyser, and a 10 L bioreactor for inoculum preparation and for preliminary viability and optimisation studies.
144L Biorecator
Bioreactor for cultures, with a net volume going from 20 to 100 L. (Bionet, model F3-100)
EQUIPMENT
144 L Bioreactor (Bionet)
10 L Bioreactor (Bionet)
Tangential microfiltration and ultrafiltration system (Bionet)
Cell disruptor (Gea Niro Soavi)
Process centrifuge (Alfa Laval)
Freeze dryer with chamber (Coolvacuum)
MANAGER
Antoni Planas Sauter, PhD
Head of GQBB Group - Professor - Fellow of the Royal Academy of Sciences and Arts of Barcelona
+34932672000
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BUSINESS SOLUTION AREAS
RESEARCH GROUP
School of Engineering
Biological and Biotechnological Chemistry
Its activity focuses on the identification and molecular analysis of proteins and enzymes as therapeutic targets, together with the design and application of enzymes in biocatalysis and biotechnology with microorganisms.