Biomaterials Osteoarthritis (Combination of tough biomaterials and nanotechnology-enabled gene therapy to regenerate cartilage)
Innovative biomaterials to regenerate cartilage and treat osteoarthritis.
Funding Sources:
Other entities
Other entities
Funding Agency:
Type of Project:
Individual project
Individual project
Period:
24/09/2022 a 24/09/2025
24/09/2022 a 24/09/2025
Funding:
291.345€
291.345€
Project current status:
ACTIVE
ACTIVE
The overall aim of this project is to combine a cartilage-mimicking biomaterial with nanoparticle enabled gene therapy to promote simultaneous osteoarthritis treatment and new cartilage production.
The objectives of the project are
1. Cartilage Replacement: Develop injectable and biocompatible materials that mimic thecompression forces of cartilage.
2. Cartilage Regeneration: Study the effects of biomaterials on cartilage production.
3. Osteoarthritis treatment: Combine the biomaterial with nanoparticle-delivered gene therapy to treat inflammation.
PRIMARY INVESTIGATOR
LINKED NEWS
Interview
Interview with Dr. Núria Oliva
06/03/2023
“In the Hydrolage project we’re seeking a treatment for osteoarthritis by combining a biomaterial to regenerate cartilage with gene therapy with RNA nanoparticles to treat inflammation.”
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Doctoral thesis
Hydrogel Dressings for Diabetic Foot Ulcer Treatment
02/09/2022
Dr José Antonio Durán defended his doctoral thesis at IQS, in which he developed dressings with hydrogels as platforms for the controlled release of miRNAs for diabetic foot ulcer treatment.
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RESEARCH GROUP
School of Engineering
Materials Engineering
Its activities focus on three main areas: the development of new functional materials, surface engineering and biomaterials.
School of Engineering
Chemical & Synthetic Biology for Biotherapies
This group combines chemistry and synthetic biology to develop precision bio-nano-therapeutics based on smart proteins and to generate molecular systems that enable transport of therapeutics to the brain.
