Biomaterials Osteoarthritis (Combination of tough biomaterials and nanotechnology-enabled gene therapy to regenerate cartilage)

The overall aim of this project is to combine a cartilage-mimicking biomaterial with nanoparticle enabled gene therapy to promote simultaneous osteoarthritis treatment and new cartilage production.

The objectives of the project are
1. Cartilage Replacement: Develop injectable and biocompatible materials that mimic thecompression forces of cartilage.
2. Cartilage Regeneration: Study the effects of biomaterials on cartilage production.
3. Osteoarthritis treatment: Combine the biomaterial with nanoparticle-delivered gene therapy to treat inflammation.