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Cristina Fornaguera Puigvert, PhD

Associate Professor
+34932672000

RESEARCH LINES

  • Polymeric nanosystems for biomedical applications.
  • Design of advanced drug delivery systems.
  • Design of non-viral vectors for gene therapy.
  • Optimisation of nanoformulations with organ-specific vectorisation.
  • Formulation of mRNA vaccines based on nanosystems.
  • Design of new immunotherapies for cancer treatment

 

MEMBER OF:

GEMAT

Grup d'Enginyeria de Materials

School of Engineering

Materials Engineering

Its activities focus on three main areas: the development of new functional materials, surface engineering and biomaterials.

ChemSynBio

CHEMICAL & SYNTHETIC BIOLOGY FOR BIOTHERAPIES

School of Engineering

Chemical & Synthetic Biology for Biotherapies

This group combines chemistry and synthetic biology to develop precision bio-nano-therapeutics based on smart proteins and to generate molecular systems that enable transport of therapeutics to the brain.

LATEST PROJECTS

DemiRNApy (Role of miRNAs in the anterior cingulate cortex, as peripheral biomarkers, and their targeted modulation by nano-tools as a antidepressant therapy)

Role of microRNAs in the brain , as peripheral biomarkers and as nano-tools as novel antidepressant therapy
Funding Agency:
Research Group Link:
Materials Engineering (GEMAT)
Chemical & Synthetic Biology for Biotherapies (ChemSynBio)

TumorOut (Innovative mRNA vaccine against lung cancer)

Innovative platform of targeted polymeric nanoparticles for efficient personalized therapy against lung cancer
Funding Agency:
Research Group Link:
Materials Engineering (GEMAT)
Chemical & Synthetic Biology for Biotherapies (ChemSynBio)

ZwiRNA (Nanopartículas zwiteriónicas como vacunas de ARNm contra el cáncer pulmonar)

Desarrollo de Nanopartículas zwiteriónicas de Poli(beta-aminoester) como vacunas de mRNA para tratar el cáncer de pulmón de células no pequeñas (zwiRNA).
Funding Agency:
Research Group Link:
Materials Engineering (GEMAT)
Chemical & Synthetic Biology for Biotherapies (ChemSynBio)
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LINKED NEWS

Doctoral thesis

Polymers for Invisible Nanoparticles in mRNA Vaccines

13/09/2023
Dr Coral García recently defended her doctoral thesis at IQS, in which she managed to develop a system of polymeric vaccines based on mRNA that are invisible to premature elimination by the immune system and ensure that they exclusively impact target cells.
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Research

New personalized therapeutic vaccine for lung cancer

07/03/2023
IQS professor Dr Cristina Fornaguera is leading the European project TumorOUT to design a new immunotherapy based on polymer nanoparticles with encapsulated antigenic mRNAs to holistically attack different mechanisms of lung cancer.
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Research

Micro RNAs to Treat Depression

09/01/2023
IQS is one of the members of the DemiRNApy project, one of the 36 research projects selected by the Fundació Marató TV3 charitable fundraising drive in its 2021 edition dedicated to mental health, with the aim of developing nanotherapies to treat depression.
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Research

Invisible, Targeted mRNA Vaccines

03/11/2022
The GEMAT group at IQS is working on the zwiRNA project with the goal of designing a new state-of-the-art therapeutic vaccine for the treatment of lung cancer.
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Interview

Interview with Dr José Rodrigo Magaña and Dr Cristina Fornaguera

10/06/2022
"My contribution to the ANTIEMT project is designing genetic material transporters. They are invisible polymers for most of the body's cells, except for tumor cells, to which they are targeted as ‘ninjas.’"
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News

Confocal Microscopy

05/02/2021
IQS has a Leica SP8 Confocal Scanning Microscope used for any application that involves the analysis of images that emit fluorescence, on their own or if they have been previously labeled with fluorophores, that allows the analysis of materials and biomaterials in addition to the analysis of biological tissues and cell culture.
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Interview

Dr Borrós and Dr Fornaguera, leaders of the CoviNanoVax project

08/01/2021
“We have our mRNA encapsulated, which appears from the outset that it will be immunogenic, stable and non-toxic, with stable nanoparticles at 4ºC, and obtained through an easily scalable process.“
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