IQS-SCIEX Demo Lab
Laboratory arising from the collaboration between SCIEX and IQS to promote research in chemical analysis techniques based on high resolution mass spectrometry. This partnership makes the availability of powerful new generation equipment possible in a university environment where research promotes the study of the analytical techniques and their application in industrial environments such as chemistry, biopharma, biotechnology, and proteomics. The cooperation between both entities includes the joint work between SCIEX experts and IQS professors and researchers.
QTOF X500B EQUIPMENT CONNECTED TO AN EXION LCAD CHROMATOGRAPH:
- Obtains a complete unbiased MS and MS/MS record from any sample with known or unknown components.
- Suitable for qualitative and quantitative analysis.
- It is used for impurity identification, characterisation of biological drugs and exact mass determination.
- Intact mass determination, capable of determining the molecular weight of proteins, based on the obtanined spectra.
- Study of the drug-antibody ratio: to verify the payload of the drug-antibody ratio and its distribution throughout the sample, through reconstructed spectra.
QTRAP 7500 EQUIPMENT CONNECTED TO AN EXION LCAD CHROMATOGRAPH:
- High robustness, high sensitivity.
- Ideal for analyses requiring maximum sensitivity in quantification at very low levels, both for small and large molecules.
- Ionisation probes: ESI and APCI mode.
QTOF X500B CONNECTED TO EXIONLCAD CHROMATOGRAPH (SCIEX)
Hybrid LC/MS/Ms quadrupole time-of-flight (QTOF) mass spectrometer, with a mass range from 5 to 2250 m/z in quadrupole mode and up to 40 kDa in QTOF mode. It is a device with sensitivities comparable to a high-performance triple quadrupole device, allowing very high scan speeds without compromising resolution and with constant mass accuracy.
EQUIPMENT
SCIEX QTOF X500B connected to an ExionLCAD chromatograph (Sciex)
SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP (Sciex)
MANAGER
RESEARCH GROUP
School of Engineering
Electrochemistry and Bioanalysis Group
EQBA's activity is structured around the different analytical, spectrometric, chromatographic, electrochemical and optical techniques, both in their application and in their development.
School of Engineering
Engineering and Simulation of Environmental Processes Group
Its activity focuses on environmental engineering and molecular and process simulation to respond to current societal challenges: climate change, water scarcity, and population growth.
LINKED NEWS
Research
Analysis of Pollutants in Reclaimed Water
12/06/2023
Researchers from IQS and IDAEA – CSIC are collaborating with the Catalan Water Agency and the Barcelona Water Company on a project to determine the chemical contaminants present in reclaimed water and evaluate their impact on living beings and public health.
READ FULL NEW
News
IQS-SCIEX: advances in high-resolution instrumentation
12/04/2023
As part of the collaboration agreement between IQS and the scientific instrumentation manufacturer SCIEX, two seminars were recently held to present the company's new high-resolution mass spectrometry (HRMS) instruments and their applications.
READ FULL NEW
Research
Pioneering Techniques for the Characterization of Oligonucleotides
09/03/2023
Researchers at IQS are conducting pioneering research in the IQS-SCIEX Demo Lab to characterize and purify nucleic acids, the active principal ingredients used to develop new strategies in medicine and therapies.
READ FULL NEW
Research
Analysis and Monitoring of Cyanotoxins
24/11/2021
The IQS Environmental Laboratory and the SCIEX_IQS Demo Lab have started to work together in the development of analytical methods for the control of cyanotoxins, using advanced HPLC-MS techniques.
READ FULL NEW
7 Questions for...
Margalida Artigues
04/10/2021
Margalida Artigues, investigadora postdoctoral de IQS Sciex Demo Lab
READ FULL NEW
IQS’s Commitment to Expoquimia
04/10/2021
IQS was present at the latest edition of Expoquimia that took place between 14 and 17 September at the Barcelona Fairgrounds.
READ FULL NEW
News
Nuevo equipo en el IQS-SCIEX Demo Lab
03/05/2021
IQS dispone de un nuevo equipo de ultra gama, SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP®, instalado en el recientemente creado IQS-SCIEX Demo Lab, que permitirá ampliar las posibilidades de investigación avanzada y la oferta de transferencia de tecnología a la industria.
READ FULL NEW
News
Analysis of nitrosamines, nitrites, and nitrates in drugs
08/01/2021
In July 2018, public health authorities became aware of the presence of the N-nitrosodimethylamine (NDMA) impurity in Valsartan batches for the first time. In the following months, other nitrosamines in drugs were detected from the same family (sartans), such as Ibersartan or Losartan, and in other drugs such as pioglitazone, ranitidine, and metformin.
READ FULL NEW
