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IQS-SCIEX Demo Lab

Laboratory arising from the collaboration between SCIEX and IQS to promote research in chemical analysis techniques based on high resolution mass spectrometry. This partnership makes the availability of powerful new generation equipment possible in a university environment where research promotes the study of the analytical techniques and their application in industrial environments such as chemistry, biopharma, biotechnology, and proteomics. The cooperation between both entities includes the joint work between SCIEX experts and IQS professors and researchers.

QTOF X500B EQUIPMENT CONNECTED TO AN EXION LCAD CHROMATOGRAPH:

  • Obtains a complete unbiased MS and MS/MS record from any sample with known or unknown components.
  • Suitable for qualitative and quantitative analysis.
  • It is used for impurity identification, characterisation of biological drugs and exact mass determination.
  • Intact mass determination, capable of determining the molecular weight of proteins, based on the obtanined spectra.
  • Study of the drug-antibody ratio: to verify the payload of the drug-antibody ratio and its distribution throughout the sample, through reconstructed spectra.

QTRAP 7500 EQUIPMENT CONNECTED TO AN EXION LCAD CHROMATOGRAPH:

  • High robustness, high sensitivity.
  • Ideal for analyses requiring maximum sensitivity in quantification at very low levels, both for small and large molecules.
  • Ionisation probes: ESI and APCI mode.

QTOF X500B CONNECTED TO EXIONLCAD CHROMATOGRAPH (SCIEX)

Hybrid LC/MS/Ms quadrupole time-of-flight (QTOF) mass spectrometer, with a mass range from 5 to 2250 m/z in quadrupole mode and up to 40 kDa in QTOF mode. It is a device with sensitivities comparable to a high-performance triple quadrupole device, allowing very high scan speeds without compromising resolution and with constant mass accuracy.

EQUIPMENT

SCIEX QTOF X500B connected to an ExionLCAD chromatograph (Sciex)

SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP (Sciex)

MANAGER

LINKED NEWS

Research

Analysis and Monitoring of Cyanotoxins

24/11/2021
The IQS Environmental Laboratory and the SCIEX_IQS Demo Lab have started to work together in the development of analytical methods for the control of cyanotoxins, using advanced HPLC-MS techniques.
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7 Questions for...

Margalida Artigues

04/10/2021
Margalida Artigues, investigadora postdoctoral de IQS Sciex Demo Lab
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Editorial

IQS’s Commitment to Expoquimia

04/10/2021
IQS was present at the latest edition of Expoquimia that took place between 14 and 17 September at the Barcelona Fairgrounds.
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News

Nuevo equipo en el IQS-SCIEX Demo Lab

03/05/2021
IQS dispone de un nuevo equipo de ultra gama, SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP®, instalado en el recientemente creado IQS-SCIEX Demo Lab, que permitirá ampliar las posibilidades de investigación avanzada y la oferta de transferencia de tecnología a la industria.
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News

Analysis of nitrosamines, nitrites, and nitrates in drugs

08/01/2021
In July 2018, public health authorities became aware of the presence of the N-nitrosodimethylamine (NDMA) impurity in Valsartan batches for the first time. In the following months, other nitrosamines in drugs were detected from the same family (sartans), such as Ibersartan or Losartan, and in other drugs such as pioglitazone, ranitidine, and metformin.
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