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Chromatography Laboratory

Laboratory dedicated to the development and optimisation of analysis methods based on chromatographic techniques. Also to the validation, transfer and analysis of chemical products in general. It has consolidated experience in the chromatographic analysis of a wide range of materials, from pharmaceuticals to environmental pollutants.

Application of chromatography (HPLC and GC) and other chemical analysis techniques to determine the composition of chemical products in general, products of the pharmaceutical and cosmetic industry, fine chemistry, food, environmental matrices, etc.

  • In raw materials, active ingredients, excipients, drugs and products of the pharmaceutical industry according to GMP requirements and internal methods, pharmacopoeia methods or methods provided by the customer
  • Determination of richness, related substances, traces and impurities
  • Residual solvents
  • Nitrosamines
  • Development and optimisation of chromatographic methods. Validation. Method transfer
  • Consulting on chromatographic techniques

 

  • Composition analysis of chemical products in general
  • Determination of siloxanes
  • Amino acid analysis
  • Fatty acids
  • Organic halogens
  • Water by Karl-Fisher
  • Nitrogen by Kjeldahl method

EQUIPMENT

Liquid chromatographs (HPLC, UPLC) with UV, diode array (DAD), fluorescence, refractive index (RI), conductimeter and mass spectrometer (MS) and triple quadrupole MS/M with ESI and APCI probe

Gas chromatographs with capillary (HRGC) and packed (GC) columns and FID, ECD, TCD, NPD, and MS detectors

Ion chromatograph with conductivity suppression

Static headspace (HS) and thermal desorption modules

Capillary electrophoresis equipment (HPCE) with DAD detector

Potentiometric titrator with different selective electrodes

Karl-Fischer Titrator

Accelerated Solvent Extractor (ASE)

Bomb calorimeter

SO2 distiller

Microkjeldahl

Conductimeter

Total organic carbon (TOC) analyser

Flash Point Testers (Penksy-Martens)

MANAGER

Ms Maria Serrat Samsó

Head of Chromatography Laboratory
+34932672000

Francesc Broto Puig, PhD

Professor
+34932672000
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BUSINESS SOLUTION AREAS

Pharmacy and cosmetics

Environment, sustainability and energy

Interlaboratory Exercises (Nuclear Power Plants)

Flow Chemistry Unit

Chemical analysis under Good Manufacturing Practices (GMP)

RESEARCH GROUP

QuAN

Química Analítica

School of Engineering

Analytical Chemistry Group

QuAN's activity is structured around the different analytical, spectrometric, chromatographic, electrochemical and optical techniques, both in their application and in their development.

LINKED NEWS

Research

Analysis of Neurotoxic Compounds in Water. COGNIRISK Project

21/01/2022
Researchers from IQS and IDAEA-CSIC collaborate in this project for the analysis of neurotoxic compounds present in water, using advanced methodologies that improve the detection of these compounds and the characterisation of their risk.
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Research

New Generation of Drugs against Neurotoxic Industrial Chemicals (NeuroTICs)

03/05/2021
Researchers from IQS are part of the NeuroTICs project, a consortium created to establish a new generation of therapeutic agents against poisoning by neurotoxic agents, as well as to determine their action, using zebrafish and rodent models for the study.
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News

Analysis of nitrosamines, nitrites, and nitrates in drugs

08/01/2021
In July 2018, public health authorities became aware of the presence of the N-nitrosodimethylamine (NDMA) impurity in Valsartan batches for the first time. In the following months, other nitrosamines in drugs were detected from the same family (sartans), such as Ibersartan or Losartan, and in other drugs such as pioglitazone, ranitidine, and metformin.
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