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Theranostic photosensitizers (Phosphorescence-guided surgery combined with photodynamic therapy)

Photodynamic therapy uses harmless light in live cells and animal to activate non- toxic photosensitive chemicals photosensitizers to generate cytotoxic species for malignant cell eradication (cancer cells, bacterial infections).

Fuente de financiación:
Generalitat de Catalunya
Entidad financiadora:
Tipología del proyecto:
Proyecto Individual
Periodo:
01/07/2022 a 01/07/2025
Financiación:
144.300€
Estado del proyecto:
ACTIVO

This project will explore the concept of theranostic agents to demonstrate its utility in the Photodynamic therapy (PDT) field and convince the medical community to include PDT as a common clinical treatment against a wide variety of diseases such as virus, bacterial or fungi infections and cancer.

The project is based on the concept that it should be possible to use the same light to induce the death of the cancer cells or pathogenic bacteria, and simultaneously measure the amount of ROS generated to avoid unnecessary damage to the surroundings tissues or visualize the remaining tumor cells after the surgery treatment to completely eradicate them. The resesarcher working in this Beatriu de Pinos Fellowship is Dr. Roger Bresolí under the supervision of Dr. Santi Nonell.

INVESTIGADOR PRINCIPAL

Dr. Roger Bresolí Obach

Profesor Asociado
+34932672000
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GRUPO DE INVESTIGACIÓN RELACIONADO

AppLightChem

Applied Photobiological Chemistry

School of Engineering

Applied Photobiological Chemistry

Investigación especializada en las aplicaciones biomédicas (resistencia antimicrobiana con fototerapia) y desarollo de teragnósticos en el diagnóstico y tratamiento de tumores